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historicalmarkerproject/markers/HMLRF_pioneering-human-genetics_Madison-WI.html
While a University of Wisconsin genetics professor from 1960 to 1988, Oliver Smithies pioneered the targeted genetic modification of mouse embryonic stem cells. This discovery led to the development of "knockout" mice, which became an indispensabl…
historicalmarkerproject/markers/HMLR9_mass-production-of-penicillin_Madison-WI.html
During World War II countless lives were saved through the use of the antibiotic penicillin, a natural product of a mold. However, the drug became widely available only after a method was developed to mass-produce it from a selected and geneticall…
historicalmarkerproject/markers/HMLPX_the-power-of-ideas_Madison-WI.html
As president of the University of Wisconsin from 1903 to 1918, Charles Van Hise championed a mission of public service that became known as the Wisconsin Idea. Calling for professors to share the wealth of their teaching and research, Van Hise dec…
historicalmarkerproject/markers/HMLNG_disease-resistant-plants_Madison-WI.html
At the end of the 19th century, a fungal infection called cabbage yellows threatened the entire Wisconsin cabbage crop. University of Wisconsin plant pathologist John C. Walker solved the problem by developing strains of cabbage resistant to the f…
historicalmarkerproject/markers/HMLNF_the-land-ethic_Madison-WI.html
The ideas of University of Wisconsin ecologist Aldo Leopold provided the intellectual and philosophical foundation for the discipline of wildlife ecology. His 1948 book of essays, A Sand County Almanac, gave form and voice to the land ethic that u…
historicalmarkerproject/markers/HMLNE_genetically-superior-crops_Madison-WI.html
University of Wisconsin geneticist R.A. Brink brought hybrid corn to Wisconsin, releasing the state's first hybrid for production in 1933. Eight years later ninety percent of Wisconsin corn was hybrid. Soon the yield per acre was tripled. Brink al…
historicalmarkerproject/markers/HMLND_preventing-endemic-goiter_Madison-WI.html
In regions distant from oceans, goiter once was a common disease of humans and animals. Goiter, manifested through an enlarged thyroid gland, is caused by a deficiency of iodine in the diet. University of Wisconsin biochemists Edwin B. Hart and Ha…
historicalmarkerproject/markers/HMLN3_first-reliable-test-of-milk-quality_Madison-WI.html
A milestone in modern dairying was the development of a simple and accurate measure of the butterfat content of milk. University of Wisconsin biochemist Stephen M. Babcock in 1890 developed the test that made him internationally famous and revolut…
historicalmarkerproject/markers/HMLMF_discovering-vitamins-and-trace-minerals_Madison-WI.html
By feeding diets of single grains to sixteen dairy heifers, University of Wisconsin scientists under the direction of biochemist E.B. Hart in 1907 set the stage for the discovery of vitamins and essential trace minerals. These feeding experiments …
historicalmarkerproject/markers/HMLK0_scientific-approach-to-agriculture_Madison-WI.html
In 1893 the College of Agriculture's emerging science-based approach to agriculture was emphatically demonstrated to farmers and Wisconsin citizens by the postmortem verification of a tuberculosis test for cattle. Organized by University of Wiscon…