The Discovery of Insulin

The Discovery of Insulin (HMO6R)

Location: Toronto, ON 44236 Toronto Division
Country: Canada
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N 43° 39.677', W 79° 23.621'

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Decouverte De L'Insuline

{The marker has a both an English and French version. In English:}

In one of the most important advances in modern medicine, a team of investigators isolated and purified insulin in a building which stood on this site. On May 17, 1921, Frederick Banting, a young surgeon, and Charles Best, a recent graduate in physiology and biochemistry, began a series of experiments on pancreatic secretions in an attempt to find a treatment for "diabetes mellitus". Working under the general direction of J.J.R. Macleod, an expert in carbohydrate metabolism, they developed a promising anti-diabetic extract. James Collip, a noted biochemist, then increased the purity and potency of the substance. With the first successful clinical test of insulin on a human diabetic on January 23, 1922, Banting, Best, Macleod and Collip ensured prolonged lives for millions of diabetics throughout the world.

Erected by the Ontario Heritage Foundation, Ministry of Culture and Communications

{In French:}
La m?decine moderne doit l'un de ses progr le plus spectaculaires a une ?quipe de chercheurs qui parvient ? isoler et a purifier l'insulin. Le 17 Mai, 1921 dans une maison qui s'?levait ici, le jeune docteur Frederick Banting et un dipl?m? en physiologie et en biochimie. Charles Best, entreprennent une s?rie d'exp?riences sur les s?cr?tions pancr?atiques, a la recherche d'un traitment du diab?te sucr?. Sous la direction d'un sp?cialiste du metabolisme des hyrdocarbonates, J.J.R. McCleod, ils con?oivent un extrait antidiab?tique prometteur dont une biochimiste r?put?, James Collip, accro?t la puret? et l'efficacite. Le 23 janvier, 1922, avec son premier succ clinique sur une diab?tique humain, l'?quipe de Banting, Best, MacLeod et Collip assure ? des millions de diab?tiques ? travers le monde un moyen de prolonger leur vie.

?rig?e par la Fondation du patrimoine ontarien, Minist?re de la Culture et des Communications
HM NumberHMO6R
Placed ByOntario Heritage Foundation
Marker ConditionNo reports yet
Date Added Thursday, September 4th, 2014 at 6:49pm PDT -07:00
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Locationbig map
UTM (WGS84 Datum)17T E 629516 N 4835507
Decimal Degrees43.66128333, -79.39368333
Degrees and Decimal MinutesN 43° 39.677', W 79° 23.621'
Degrees, Minutes and Seconds43° 39' 40.62" N, 79° 23' 37.26" W
Driving DirectionsGoogle Maps
Area Code(s)330, 234
Closest Postal AddressAt or near 1 King's College Cir, Toronto ON 44236, CA
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